The trophoblast as an integral component of a macrophage-cytokine network.

@article{Guilbert1993TheTA,
  title={The trophoblast as an integral component of a macrophage-cytokine network.},
  author={Larry J. Guilbert and Sarah A Robertson and Thomas Wegmann},
  journal={Immunology and cell biology},
  year={1993},
  volume={71 ( Pt 1)},
  pages={
          49-57
        }
}
The trophoblast, an epithelial cell of fetal origin that forms the physical barrier between the mother and developing conceptus, becomes a component of the host immune system during pregnancy. Of the classical immune cells, it most closely resembles the macrophage, also present in high numbers in the pregnant uterus. The macrophage and trophoblast, as cell classes, share characteristics such as phagocytosis, syncytialization, invasiveness, expression of the proteins CD4, CD14, IgG receptor (FcR… CONTINUE READING