The tripeptide phenylalanine-(d) glutamate-(d) glycine modulates leukocyte infiltration and oxidative damage in rat injured spinal cord

@article{Bao2006TheTP,
  title={The tripeptide phenylalanine-(d) glutamate-(d) glycine modulates leukocyte infiltration and oxidative damage in rat injured spinal cord},
  author={F. Bao and S. John and Y. Chen and R. Mathison and L. Weaver},
  journal={Neuroscience},
  year={2006},
  volume={140},
  pages={1011-1022}
}
  • F. Bao, S. John, +2 authors L. Weaver
  • Published 2006
  • Chemistry, Medicine
  • Neuroscience
  • The tripeptide, phenylalanine-glutamate-glycine (FEG) and its d-isomeric form phenylalanine-(D) glutamate-(D) glycine (feG), derived from submandibular gland peptide-T, significantly reduce the allergic inflammatory response and leukocyte trafficking and neutrophil migration into intestine, heart and lungs. Due to these actions, we hypothesized that feG would attenuate the early inflammatory response to spinal cord injury, reduce free radical production and improve neurological outcomes, like… CONTINUE READING
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