The tripeptide feG reduces endotoxin‐provoked perturbation of intestinal motility and inflammation

@article{Mathison2001TheTF,
  title={The tripeptide feG reduces endotoxin‐provoked perturbation of intestinal motility and inflammation},
  author={R. Mathison and P. Lo and D. Tan and B. Scott and J. Davison},
  journal={Neurogastroenterology & Motility},
  year={2001},
  volume={13}
}
  • R. Mathison, P. Lo, +2 authors J. Davison
  • Published 2001
  • Biology, Medicine
  • Neurogastroenterology & Motility
  • Lipopolysaccharide (LPS)‐induced intestinal endotoxaemia perturbs motility and causes activation and influx of inflammatory cells into the muscle tissue. Because rat submandibular gland peptide T (SGP‐T; Thr‐Asp‐Ile‐Phe‐Glu‐Gly‐Gly), its carboxyl‐terminal fragment tripeptide, FEG (Phe‐Glu‐Gly) and its D‐isomeric analogue, feG, modulate intestinal anaphylactic reactions, we examined whether these peptides also modulate LPS‐induced intestinal endotoxaemia in conscious rats. The disruption of the… CONTINUE READING
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