The treatment of spasticity by intrathecal administration of baclofen: a preliminary personal experience.

Abstract

The administration of baclofen, a GABAb agonist, by direct infusion into the CSF by means of a programmable device, may avoid the undesired side effects of the oral administration of both the same and other antispastic drugs while giving a marked reduction of spasticity. The preliminary results on 12 patients show the total efficacy of this procedure in reducing spasticity markedly.

Cite this paper

@article{Broggi1993TheTO, title={The treatment of spasticity by intrathecal administration of baclofen: a preliminary personal experience.}, author={Giovanni Broggi and Domenico Servello and Stacia Brock and Ivano Dones}, journal={Journal of neurosurgical sciences}, year={1993}, volume={37 4}, pages={203-8} }