The treatment of postanaesthetic shivering: a double blind comparison between alfentanil and pethidine

@article{Lyons1995TheTO,
  title={The treatment of postanaesthetic shivering: a double blind comparison between alfentanil and pethidine},
  author={B. Lyons and M. Carroll and N. McDonald},
  journal={Acta Anaesthesiologica Scandinavica},
  year={1995},
  volume={39}
}
  • B. Lyons, M. Carroll, N. McDonald
  • Published 1995
  • Medicine
  • Acta Anaesthesiologica Scandinavica
  • It has been postulated that pethidine may mediate its effects on postanaesthetic shivering (PAS) via kappa‐opioid receptors. However, clinical evidence indicates that alfentanil, a pure ma‐agonist, may also have beneficial effects on PAS. In order to assess whether opioid effects on PAS are effected via kappa receptors, fifty‐one patients were randomised to receive alfentanil 250 μg (n=18), pethidine 25 mg (n=18) or placebo (n=15) on a double‐blind basis for the treatment of established… CONTINUE READING
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