The transmission dynamics of groups A and B human respiratory syncytial virus (hRSV) in England & Wales and Finland: seasonality and cross-protection.

@article{White2005TheTD,
  title={The transmission dynamics of groups A and B human respiratory syncytial virus (hRSV) in England & Wales and Finland: seasonality and cross-protection.},
  author={Lisa J. White and Matti E. Waris and Patricia A. Cane and D. James Nokes and Graham F Medley},
  journal={Epidemiology and infection},
  year={2005},
  volume={133 2},
  pages={279-89}
}
Human respiratory syncytial virus (hRSV) transmission dynamics are inherently cyclical, and the observed genetic diversity (between groups A and B) also appears to have a repeating pattern. A key unknown is the extent to which genetic variants interact immunologically, and thus impact on epidemiology. We developed a novel mathematical model for hRSV transmission including seasonal forcing of incidence and temporary intra- and inter-group partial immunity. Simultaneous model fits to data from… CONTINUE READING

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