The translocon: a dynamic gateway at the ER membrane.

  title={The translocon: a dynamic gateway at the ER membrane.},
  author={Arthur E. Johnson and Michael van Waes},
  journal={Annual review of cell and developmental biology},
Cotranslational protein translocation across and integration into the membrane of the endoplasmic reticulum (ER) occur at sites termed translocons. Translocons are composed of several ER membrane proteins that associate to form an aqueous pore through which secretory proteins and lumenal domains of membrane proteins pass from the cytoplasm to the ER lumen… CONTINUE READING