The translocation of fullerenic nanoparticles into lysosome via the pathway of clathrin-mediated endocytosis.

@article{Li2008TheTO,
  title={The translocation of fullerenic nanoparticles into lysosome via the pathway of clathrin-mediated endocytosis.},
  author={Wei Li and Chunying Chen and Chang Ye and Taotao Wei and Yuliang Zhao and F. Y. Lao and Zhen Troy Chen and Huan Meng and Yuxi Gao and Hui Yuan and Genmei Xing and Feng Zhao and Zhifang Chai and Xujia Zhang and Fuyu Yang and Dong Han and Xianhua Tang and Yingge Zhang},
  journal={Nanotechnology},
  year={2008},
  volume={19 14},
  pages={
          145102
        }
}
Manufactured fullerene nanoparticles easily enter into cells and hence have been rapidly developed for biomedical uses. However, it is generally unknown which route the nanoparticles undergo when crossing cell membranes and where they localize to the intracellular compartments. Herein we have used both microscopic imaging and biological techniques to explore the processes of [C(60)(C(COOH)(2))(2)](n) nanoparticles across cellular membranes and their intracellular translocation in 3T3 L1 and RH… CONTINUE READING

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Nanotoxicology (California: American Scientific Publishers

Y LZhao, H SNalwa
  • 2006
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