The translational landscape of the mammalian cell cycle.

  title={The translational landscape of the mammalian cell cycle.},
  author={Craig R. Stumpf and Melissa V. Moreno and Adam B. Olshen and Barry S. Taylor and Davide Ruggero},
  journal={Molecular cell},
  volume={52 4},
Gene regulation during cell-cycle progression is an intricately choreographed process, ensuring accurate DNA replication and division. However, the translational landscape of gene expression underlying cell-cycle progression remains largely unknown. Employing genome-wide ribosome profiling, we uncover widespread translational regulation of hundreds of mRNAs serving as an unexpected mechanism for gene regulation underlying cell-cycle progression. A striking example is the S phase translational… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 9 times over the past 90 days. VIEW TWEETS
69 Citations
29 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 69 extracted citations


Publications referenced by this paper.
Showing 1-10 of 29 references

Similar Papers

Loading similar papers…