The translation initiation factor, PeIF5B, from Pisum sativum displays chaperone activity.

@article{Suragani2011TheTI,
  title={The translation initiation factor, PeIF5B, from Pisum sativum displays chaperone activity.},
  author={Madhuri Suragani and Sheeba Rasheedi and Seyed E. Hasnain and Nasreen Zafar Ehtesham},
  journal={Biochemical and biophysical research communications},
  year={2011},
  volume={414 2},
  pages={390-6}
}
We earlier documented the structural and functional characterization of PeIF5B factor from Pisum sativum that shows strong homology to the universal translation initiation factor eIF5B (Rasheedi et al., 2007, 2010 [12,13]). We now show that PeIF5B is an unusually thermo-stable protein resisting temperatures up to 95 °C. PeIF5B prevents thermal aggregation of heat labile proteins, such as citrate synthase (CS) and NdeI, under heat stress or chemical denaturation conditions and promotes their… CONTINUE READING