The translation elongation factor eEF1B plays a role in the oxidative stress response pathway.

@article{Olarewaju2004TheTE,
  title={The translation elongation factor eEF1B plays a role in the oxidative stress response pathway.},
  author={Olubunmi Olarewaju and Pedro A. Ortiz and Wasimul Q. Chowdhury and Ishita Chatterjee and Terri Goss Kinzy},
  journal={RNA biology},
  year={2004},
  volume={1 2},
  pages={89-94}
}
The multi-subunit guanine nucleotide exchange factor eEF1B for Saccharomyces cerevisiae Translation Elongation Factor 1A (eEF1A) has catalytic (eEF1Balpha) and noncatalytic (eEF1Bgamma) subunits. Deletion of the two nonessential genes encoding eEF1Bgamma has no dramatic effects on total protein synthesis or translational fidelity. Instead, loss of each gene gives resistance to oxidative stress, and loss of both is additive. The level of stress resistance is similar to overexpression of the… CONTINUE READING
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