The transfer of anti-human immunodeficiency virus nucleoside compounds by the term human placenta.

@article{Bawdon1992TheTO,
  title={The transfer of anti-human immunodeficiency virus nucleoside compounds by the term human placenta.},
  author={Roger E. Bawdon and Sohrab Sobhi and Jody Dax},
  journal={American journal of obstetrics and gynecology},
  year={1992},
  volume={167 6},
  pages={1570-4}
}
OBJECTIVE The purpose of this study was to compare the maternal-fetal placental transfer of 2',3'-dideoxyinosine and 2',3'-dideoxycytidine with that of 3'-azido-2', 3-dideoxythymidine (azidothymidine). STUDY DESIGN The perfusion system used carbon 14-labeled antipyrine as a reference compound to determine the clearance index of each compound. The inhibitor dipyridamole and the endogenous bases were used to determine if these anti-human immunodeficiency virus compounds crossed the placenta… CONTINUE READING
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