The transcription factor Spi-B is expressed in plasmacytoid DC precursors and inhibits T-, B-, and NK-cell development.

Abstract

Human plasmacytoid dendritic cells (pDCs), also called type 2 dendritic cell precursors or natural interferon (IFN)-producing cells, represent a cell type with distinctive phenotypic and functional features. They are present in the thymus and probably share a common precursor with T and natural killer (NK) cells. In an effort to identify genes that control… (More)

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@article{Schotte2003TheTF, title={The transcription factor Spi-B is expressed in plasmacytoid DC precursors and inhibits T-, B-, and NK-cell development.}, author={Remko Schotte and M C Rissoan and Nathalie Bendriss-Vermare and J M Bridon and Thomas Duhen and Kees Weijer and Francine Bri{\`e}re and Hergen Spits}, journal={Blood}, year={2003}, volume={101 3}, pages={1015-23} }