The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cells

@article{ermk2010TheTF,
  title={The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cells},
  author={Vladim{\'i}r {\vC}erm{\'a}k and Jan Kosla and Jiri Plachy and Kateřina Trejbalov{\'a} and Jiřı́ Hejnar and Michal Dvoř{\'a}k},
  journal={Cellular and Molecular Life Sciences},
  year={2010},
  volume={67},
  pages={3557-3568}
}
Metastatic spreading of cancer cells is a highly complex process directed primarily by the interplay between tumor microenvironment, cell surface receptors, and actin cytoskeleton dynamics. To advance our understanding of metastatic cancer dissemination, we have developed a model system that is based on two v-src transformed chicken sarcoma cell lines—the highly metastatic parental PR9692 and a non-metastasizing but fully tumorigenic clonal derivative PR9692-E9. Oligonucleotide microarray… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES

Roles of TGFbeta in metastasis

D Padua, J Massague
  • Cell Res
  • 2009
VIEW 1 EXCERPT