The toxin helothermine affects potassium currents in newborn rat cerebellar granule cells

@article{Nobile1994TheTH,
  title={The toxin helothermine affects potassium currents in newborn rat cerebellar granule cells},
  author={Mario Nobile and Valeria Magnelli and Laura Lagostena and J. Mochca-Morales and Lourival Domingos Possani and Gianfranco Prestipino},
  journal={The Journal of Membrane Biology},
  year={1994},
  volume={139},
  pages={49-55}
}
Helothermine, a recently isolated toxin from the venom of the Mexican beaded lizard Heloderma horridum horridum was tested on K+ currents of newborn rat cerebellar granule cells. In whole-cell voltageclamp experiments, cerebellar granule neurons exhibited at least two different K+ current components: a first transient component which is similar to an I A-type current, is characterized by fast activating and inactivating kinetics and blocked by 4-aminopyridine; a second component which is… CONTINUE READING

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Nucleoside composition of Heloderma venoms.

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