The toxicology of chemical interactions during pregnancy in the mouse: caffeine and phenytoin.

Abstract

The toxic interaction of caffeine and phenytoin during pregnancy was investigated in mice of the ICR strain on E10 of gestation. Caffeine, over a range of dosages, showed limited embryotoxic activity. Phenytoin was also weakly teratogenic and dosages needed to elicit embryotoxicity were accompanied by a significant increase in maternal lethality… (More)

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Cite this paper

@article{Skalko1984TheTO, title={The toxicology of chemical interactions during pregnancy in the mouse: caffeine and phenytoin.}, author={Richard G. Skalko and Priv.-Doz. Dr. med. Reinhard Poche and Thomas E Kwasigroch}, journal={Toxicology}, year={1984}, volume={30 1}, pages={7-16} }