• DOI:10.1016/0009-2797(78)90043-1
Corpus ID: 26099798

The toxicity of thallium(I) to cardiac and skeletal muscle.

@article{Hughes1978TheTO,
  title={The toxicity of thallium(I) to cardiac and skeletal muscle.},
  author={M. Hughes and W. Man and B. Whaler},
  journal={Chemico-biological interactions},
  year={1978},
  volume={23 1},
  pages={
          85-97
        }
}

M. Hughes, W. Man, B. Whaler

Published 1978

Chemistry, Medicine

Chemico-biological interactions

The effects of (a) partial or complete replacement of K+ by Tl+ in saline perfusing isolated rat heart and diaphragm preparations and (b) pulse injections of high concentrations of Tl+ or K+, have been studied. The immediate effect of Tl+ resembles that of higher concentrations of K+ and may reflect its more rapid penetration into the tissue. Tl+ appears to replace K+ on a 1:1 basis to an extent dependent upon the relative abundance of the two cations in the perfusion solution. However… CONTINUE READING

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