The toxicity of some quassinoids from Eurycoma longifolia.

  title={The toxicity of some quassinoids from Eurycoma longifolia.},
  author={K T Chan and C. L. Choo},
  journal={Planta medica},
  volume={68 7},
The 50 % aqueous ethanol extract of Eurycoma longifolia Jack (Simaroubaceace) roots was partitioned with diethyl ether, n-butanol and then water. Acute toxicity studies of each fraction on mice administered orally and brine shrimps revealed that the n-butanol fraction was the most toxic. Toxicity-guided chromatographic fractionation of the n-butanol fraction identified eurycomanone as the most toxic component. 13,21-Dihydroeurycoma-none, eurycomanol, longilactone, 14,15 beta… CONTINUE READING

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