The toxicity of organoarsenic-based warfare agents: in vitro and in vivo studies.

@article{Henriksson1996TheTO,
  title={The toxicity of organoarsenic-based warfare agents: in vitro and in vivo studies.},
  author={J{\"o}rgen Henriksson and Anders Johannisson and P-A. Bergqvist and Leif Norrgren},
  journal={Archives of environmental contamination and toxicology},
  year={1996},
  volume={30 2},
  pages={213-9}
}
The four arsenic-containing chemical warfare agents (CWA) Adamsite (technical, 10-chloro-9-10-dihydrophenarsazine), Clark 1 (Diphenyl arsine chloride), Clark 2 (Diphenyl arsine cyanide), and Lewisite (2-chloro-ethenyl dichloro arsine) were evaluated toxicologically using an in vitro and an in vivo model. The CWA were tested in vitro, using human leucocytes, in order to evaluate their effects on cell proliferation and cell cycle kinetics assayed by flow cytometry. The concentration for total… CONTINUE READING