The total mesorectal excision specimen for rectal cancer: a review of its pathological assessment.

  title={The total mesorectal excision specimen for rectal cancer: a review of its pathological assessment.},
  author={Jeremy R. Parfitt and David Kevin Driman},
  journal={Journal of clinical pathology},
  volume={60 8},
Total mesorectal excision (TME) refers to the surgical removal of the complete perirectal soft tissue envelope, using sharp instruments under direct vision, and has become the contemporary standard of care for patients with rectal cancer. Pathologists play a key role in the evaluation of these specimens, including the quality assurance of surgical performance, as well as evaluation of the circumferential radial margin (CRM). While the latter is the most significant predictor of local recurrence… CONTINUE READING
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