The topography of cell loss from locus caeruleus in Alzheimer's disease.

@article{Marcyniuk1986TheTO,
  title={The topography of cell loss from locus caeruleus in Alzheimer's disease.},
  author={Borys Marcyniuk and David M A Mann and P. O. Yates},
  journal={Journal of the neurological sciences},
  year={1986},
  volume={76 2-3},
  pages={335-45}
}
A topographical analysis of nerve cell loss from locus caeruleus in Alzheimer's disease has shown that cell loss is confined to the dorsal areas and occurs uniformly throughout the rostrocaudal length of the locus. By contrast there is no significant cell loss from ventral parts of the locus, at any point along its rostrocaudal length. Dorsally located neurones of the locus project to cerebral cortex; ventrally located neurones to non-cortical areas such as basal ganglia, cerebellum and spinal… CONTINUE READING
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