The toll-like receptor pathway: a novel mechanism of infection-induced carcinogenesis of prostate epithelial cells.

@article{Kundu2008TheTR,
  title={The toll-like receptor pathway: a novel mechanism of infection-induced carcinogenesis of prostate epithelial cells.},
  author={Shilajit D. Kundu and Chung Ryul Lee and Benjamin K. Billips and Geoffrey M Habermacher and Qiang Zhang and Victoria M Liu and Larry Y. Wong and David Jichael Klumpp and Praveen Thumbikat},
  journal={The Prostate},
  year={2008},
  volume={68 2},
  pages={223-9}
}
BACKGROUND Inflammation and infection have been linked to the pathogenesis of many cancers including prostate cancer. Components of bacteria and viruses have been identified within pathological specimens of men with prostate cancer. METHODS We characterized the in vitro response of benign prostate epithelial cells to components of infectious agents as they relate to toll-like receptors. RESULTS Primary and immortalized prostate epithelial cells (RWPE) exhibited increased proliferation in… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 63 extracted citations

Similar Papers

Loading similar papers…