The tissue factor pathway in disseminated intravascular coagulation.

  title={The tissue factor pathway in disseminated intravascular coagulation.},
  author={Bjarne \Osterud and Eirik Bj\orklid},
  journal={Seminars in thrombosis and hemostasis},
  volume={27 6},
In most instances, tissue factor (TF) exposed to the circulation is the sole culprit underlying the initiation of disseminated intravascular coagulation (DIC), although notable exceptions because of a more direct activation of the coagulation system, by snake venoms, for example, do occur. Peripheral monocytes and subendothelial structures are the potential sources of such TF; in the former, TF emerges on the cell surface on synthesis induction and in the latter it becomes available subsequent… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 52 extracted citations

Years Lost in Anesthesia Theory

View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…