The timing of the S phase and other nuclear events in yeast meiosis.

@article{Williamson1983TheTO,
  title={The timing of the S phase and other nuclear events in yeast meiosis.},
  author={Donald H. Williamson and L. H. Johnston and D. J. Fennell and G Simchen},
  journal={Experimental cell research},
  year={1983},
  volume={145 1},
  pages={209-17}
}
The length of the premeiotic S phase in individual cells of a homothallic strain of Saccharomyces cerevisiae was determined by pulse-labelling synchronously sporulating cultures with [3H]adenine and following changes in the frequency of cells in S by DNA-specific whole cell autoradiography. The average S phase was found to be at least 2-3 times as long as in mitotic diploids, and it was concluded that activation of replication origins in meiosis is considerably staggered. The timing of S in… CONTINUE READING