The timing of multiple retrieval events can alter GluR1 phosphorylation and the requirement for protein synthesis in fear memory reconsolidation.

@article{Jarome2012TheTO,
  title={The timing of multiple retrieval events can alter GluR1 phosphorylation and the requirement for protein synthesis in fear memory reconsolidation.},
  author={Timothy J Jarome and Janine L. Kwapis and Craig T Werner and Ryan G Parsons and Georgette M. Gafford and Fred J. Helmstetter},
  journal={Learning & memory},
  year={2012},
  volume={19 7},
  pages={300-6}
}
Numerous studies have indicated that maintaining a fear memory after retrieval requires de novo protein synthesis. However, no study to date has examined how the temporal dynamics of repeated retrieval events affect this protein synthesis requirement. The present study varied the timing of a second retrieval of an established auditory fear memory and followed this second retrieval with infusions of the protein synthesis inhibitor anisomycin (ANI) into the basolateral amygdala. Results indicated… CONTINUE READING
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The rat brain in stereotaxic coordinates, 4th ed

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