The timing of channel opening during miniature end-plate currents

  title={The timing of channel opening during miniature end-plate currents},
  author={I. Cohen and W. Kloot and D. Attwell},
  journal={Brain Research},
  • I. Cohen, W. Kloot, D. Attwell
  • Published 1981
  • Medicine
  • Brain Research
  • Many chemical transmitters act by opening channels with exponentially distributed life-times. We present a way to analyze a synaptic current in terms of its component channels. We can estimate the numbers and times of channel opening within the synaptic current. This approach is used to study miniature end-plate currents (m.e.p.c.s) at the frog neuromuscular junction. The results support the idea that some transmitter rebinds after dissociation from post-synaptic receptors, and suggest that the… CONTINUE READING
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