The timing of channel opening during miniature end-plate currents
@article{Cohen1981TheTO, title={The timing of channel opening during miniature end-plate currents}, author={I. Cohen and W. Kloot and D. Attwell}, journal={Brain Research}, year={1981}, volume={223}, pages={185-189} }
Many chemical transmitters act by opening channels with exponentially distributed life-times. We present a way to analyze a synaptic current in terms of its component channels. We can estimate the numbers and times of channel opening within the synaptic current. This approach is used to study miniature end-plate currents (m.e.p.c.s) at the frog neuromuscular junction. The results support the idea that some transmitter rebinds after dissociation from post-synaptic receptors, and suggest that the… CONTINUE READING
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