The timing between skeletal muscle myoblast replication and fusion into myotubes , and the stability of regenerated dystrophic myofibres : an autoradiographic study in mdx mice

@inproceedings{JOHNK1999TheTB,
  title={The timing between skeletal muscle myoblast replication and fusion into myotubes , and the stability of regenerated dystrophic myofibres : an autoradiographic study in mdx mice},
  author={M JOHNK. and GEACHIE},
  year={1999}
}
  • M JOHNK., GEACHIE
  • Published 1999
In mdx mice, a model for Duchenne muscular dystrophy, the timing between the replication of myoblasts and their incorporation into myotubes was determined autoradiographically. Thirty-eight mdx mice aged 23 d were injected with tritiated thymidine to label myoblasts replicating early in the dystrophic process. At intervals from 8 h to 30 d after injection the tibialis anterior muscles were removed, processed for autoradiography and analysed for labelled central myonuclei (derived from the… CONTINUE READING

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