The time of appearance and disappearance of fetal DNA from the maternal circulation.

@article{Thomas1995TheTO,
  title={The time of appearance and disappearance of fetal DNA from the maternal circulation.},
  author={Martyn Rhys Thomas and Boris Tutschek and Adam Frost and C. H. Rodeck and Nahid Yazdani and Ian W. Craft and Robert Williamson},
  journal={Prenatal diagnosis},
  year={1995},
  volume={15 7},
  pages={
          641-6
        }
}
A single copy Y-chromosome DNA sequence was amplified using the polymerase chain reaction (PCR) from the peripheral blood of 30 women who had achieved a pregnancy through an in vitro fertilization (IVF) programme. The time of conception was known precisely and was confirmed by serial ultrasound scans. Conceptions were dated as the number of weeks after fertilization plus 2, to give a time equivalent to the obstetric menstrual dating of the pregnancy (LMP). Y-chromosome-specific DNA was detected… CONTINUE READING
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