The time course of the humoral immune response to rhinovirus infection.

@article{Barclay1989TheTC,
  title={The time course of the humoral immune response to rhinovirus infection.},
  author={W S Barclay and W al-Nakib and Peter Gerard Higgins and David A. J. Tyrrell},
  journal={Epidemiology and infection},
  year={1989},
  volume={103 3},
  pages={659-69}
}
The specific humoral immune response of 17 volunteers to infection with human rhinovirus type 2 (HRV-2) has been measured both by neutralization and by ELISA. Six volunteers who had HRV-2-specific antibodies in either serum or nasal secretions before HRV-2 inoculation were resistant to infection and illness. Of the remaining 11 volunteers who had little pre-existing HRV-2-specific antibody, one was immune but 10 became infected and displayed increases in HRV-2-specific antibodies. These… CONTINUE READING

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