The tight relationship between papillary thyroid cancer, autoimmunity and inflammation: clinical and molecular studies.

@article{Muzza2010TheTR,
  title={The tight relationship between papillary thyroid cancer, autoimmunity and inflammation: clinical and molecular studies.},
  author={Marina Muzza and Debora Degl'innocenti and Carla Colombo and Michela Perrino and Elena Ravasi and Stefania Rossi and Valentina Cirello and Paolo Beck-Peccoz and Maria Grazia Borrello and Laura Fugazzola},
  journal={Clinical endocrinology},
  year={2010},
  volume={72 5},
  pages={702-8}
}
OBJECTIVE The recent concept that oncogenes responsible for thyroid neoplastic transformation are able to elicit an inflammatory protumourigenic microenvironment raises interest in further studies on papillary thyroid cancer (PTC) associated with thyroid autoimmunity. PATIENTS The clinical and molecular features, and the expression of inflammation-related genes, were investigated in a large series of PTCs with and without associated thyroiditis (groups A, n = 128 and B, n = 215). RESULTS… CONTINUE READING

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