The tight junction: a multifunctional complex.

@article{Schneeberger2004TheTJ,
  title={The tight junction: a multifunctional complex.},
  author={Eveline E. Schneeberger and Robert D. Lynch},
  journal={American journal of physiology. Cell physiology},
  year={2004},
  volume={286 6},
  pages={
          C1213-28
        }
}
Multicellular organisms are separated from the external environment by a layer of epithelial cells whose integrity is maintained by intercellular junctional complexes composed of tight junctions, adherens junctions, and desmosomes, whereas gap junctions provide for intercellular communication. The aim of this review is to present an updated overview of recent developments in the area of tight junction biology. In a relatively short time, our knowledge of the tight junction has evolved from a… 
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TLDR
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TLDR
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TLDR
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TLDR
New insights into the molecular architecture of tight junctions allow us to now discuss the structure and functions of this unique cell–cell adhesion apparatus in molecular terms.
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