The thymus during HIV disease: role in pathogenesis and in immune recovery.

@article{Ye2004TheTD,
  title={The thymus during HIV disease: role in pathogenesis and in immune recovery.},
  author={Ping Ye and Denise E. Kirschner and Athena P. Kourtis},
  journal={Current HIV research},
  year={2004},
  volume={2 2},
  pages={177-83}
}
The thymus is the primary lymphoid organ supplying new lymphocytes to the periphery. Clinical and morphologic studies of HIV-infected children and adults indicate that the thymus is affected by HIV. Thymic dysfunction and thymic involution occur during HIV disease and have been associated with rapid progression in infants infected perinatally with HIV. In vitro information of thymic organ culture, thymic epithelial cell culture, the SCID-hu mouse system and SHIV infection of primates have… CONTINUE READING
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