The thymidine-14C and -3H double-labeling technic in the study of the cell cycle of L1210 leukemia ascites tumor in vivo.

  title={The thymidine-14C and -3H double-labeling technic in the study of the cell cycle of L1210 leukemia ascites tumor in vivo.},
  author={Robert H. Young and Vincent T Devita and Steve Perry},
  journal={Cancer research},
  volume={29 8},
A study was performed to evaluate the double-labeling technic with thymidineA4C and -3H in the determination of the duration of DNA synthesis, duration of mitosis, and generation time of L1210 leukemia ascites tumor. The results were comparable with data obtained from labeled mitoses curves. The average duration of DNA synthesis was 9.0 hours, and the average duration of mitosis was 0.20 hours. Prolongation of generation time on the seventh day of tumor growth (18.1 hours) compared with the… CONTINUE READING

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