The thromboxane/endoperoxide receptor (TP): the common villain.

  title={The thromboxane/endoperoxide receptor (TP): the common villain.},
  author={Michel F{\'e}l{\'e}tou and Paul Michel Vanhoutte and Tony J. Verbeuren},
  journal={Journal of cardiovascular pharmacology},
  volume={55 4},
The stimulation of thromboxane/endoperoxide receptors (TP) elicits diverse physiological/pathophysiological reactions, including platelet aggregation and contraction of vascular smooth muscle. Furthermore, the activation of endothelial TP promotes the expression of adhesion molecules and favors adhesion and infiltration of monocytes/macrophages. In various cardiovascular diseases, endothelial dysfunction is predominantly the result of the release of endothelium-derived contracting factors that… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 18 extracted citations

Molecular biology of atherosclerosis.

Physiological reviews • 2013
View 20 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…