The thrombospondins.

@article{Adams2011TheT,
  title={The thrombospondins.},
  author={Josephine C. Adams and Jack W Lawler},
  journal={Cold Spring Harbor perspectives in biology},
  year={2011},
  volume={3 10},
  pages={
          a009712
        }
}
Thrombospondins are evolutionarily conserved, calcium-binding glycoproteins that undergo transient or longer-term interactions with other extracellular matrix components. They share properties with other matrix molecules, cytokines, adaptor proteins, and chaperones, modulate the organization of collagen fibrils, and bind and localize an array of growth factors or proteases. At cell surfaces, interactions with an array of receptors activate cell-dependent signaling and phenotypic outcomes… CONTINUE READING
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