The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (epsilon-caprolactone)/collagen fibers and hyaluronic acid hydrogel.

@article{Ekaputra2011TheTV,
  title={The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (epsilon-caprolactone)/collagen fibers and hyaluronic acid hydrogel.},
  author={Andrew Krishna Ekaputra and Glenn D. Prestwich and Simon M Cool and Dietmar Werner Hutmacher},
  journal={Biomaterials},
  year={2011},
  volume={32 32},
  pages={8108-17}
}
A significant stumbling block in the creation of functional three-dimensional (3D) engineered tissues is the proper vascularization of the constructs. Furthermore, in the context of electrospinning, the development of 3D constructs using this technique has been hindered by the limited infiltration of cells into their structure. In an attempt to address these issues, a hybrid mesh of poly (ɛ-caprolactone)-collagen blend (PCL/Col) and hyaluronic acid (HA) hydrogel, Heprasil™ was created via a… CONTINUE READING
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