The three-dimensional structures of methanol dehydrogenase from two methylotrophic bacteria at 2.6-A resolution.

@article{Xia1992TheTS,
  title={The three-dimensional structures of methanol dehydrogenase from two methylotrophic bacteria at 2.6-A resolution.},
  author={Z X Xia and Wei Wei Dai and Jian Xiong and Zhang Hao and Victor L Davidson and Scott A White and F. Scott Mathews},
  journal={The Journal of biological chemistry},
  year={1992},
  volume={267 31},
  pages={22289-97}
}
The structures of methanol dehydrogenase (MEDH) from two closely related methylotrophic bacteria, Methylophilus methylotrophus and W3A1, have been determined at 2.6-A resolution. The molecule, a quinoprotein of molecular mass of about 138 kDa, contains two heavy (H) and two light (L) subunits of unknown sequence and two molecules of noncovalently associated pyrroloquinoline quinone. The two enzymes crystallize isomorphously in space group P2(1) with one H2L2 heterotetramer in the asymmetric… CONTINUE READING