The three-dimensional structure of the cytostome-cytopharynx complex of Trypanosoma cruzi epimastigotes

  title={The three-dimensional structure of the cytostome-cytopharynx complex of Trypanosoma cruzi epimastigotes},
  author={Carolina de Lima Alcantara and Juliana C Vidal and Wanderley de Souza and Narcisa L Cunha-E-Silva},
  journal={Journal of Cell Science},
  pages={2227 - 2237}
ABSTRACT The cytostome-cytopharynx complex is the main site of endocytosis of Trypanosoma cruzi epimastigotes. Little is known about the detailed morphology of this remarkable structure. We used serial electron tomography and focused-ion-beam scanning electron microscopy to reconstruct the entire complex, including the surrounding cytoskeleton and vesicles. Focusing on cells that had taken up gold-labeled tracers, we produced three-dimensional snapshots of the process of endocytosis. The… 

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