The three-dimensional structure of the central region in a synaptonemal complex: a comparison between rat and two insect species,Drosophila melanogaster andBlaps cribrosa

@article{Schmekel2004TheTS,
  title={The three-dimensional structure of the central region in a synaptonemal complex: a comparison between rat and two insect species,Drosophila melanogaster andBlaps cribrosa},
  author={K. Schmekel and U. Skoglund and B. Daneholt},
  journal={Chromosoma},
  year={2004},
  volume={102},
  pages={682-692}
}
The highly ordered central region of the synaptonemal complex (SC) inBlaps cribrosa has recently been studied by electron microscope tomography (EMT), and a simple three-dimensional model presented. Using the same experimental approach we have now compared the central region inBlaps with the central regions inDrosophila melanogaster and rat. In all three species, the SCs exhibit a central element (CE) flanked by two lateral elements (LEs). The central region between the two LEs is crossed by… Expand

Figures from this paper

The central region of the synaptonemal complex inBlaps cribrosa studied by electron microscope tomography
TLDR
It is proposed that a TF with the two associated short pillars represents the structural unit in the central region and is accomplished by linking adjacent pillars to each other into the well-defined three-dimensional organization of the CE. Expand
Juxtaposition of C(2)M and the transverse filament protein C(3)G within the central region of Drosophila synaptonemal complex.
  • L. Anderson, S. Royer, +4 authors R. Hawley
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2005
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The Ultrastructure of the Synaptonemal Complexes in Galleria mellonella (Lepidoptera) Spermatocytes
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Fine structure of synaptonemal complexes was investigated in primary spermatocytes of Galleria mellonella testes in longitudinal sections and two electron dense axial or lateral elements were clearly distinguished in fine structure of the SCs. Expand
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TLDR
These SC-like structures provide insight into the rules for building and maintaining the SC by offering an 'in vivo laboratory' for models of SC assembly, structure, and disassembly. Expand
Organization of the Synaptonemal Complex During Meiosis in Caenorhabditis elegans
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A model of how the SYP proteins link the homologous axes to provide the conserved structure and width of the SC in Caenorhabditis elegans is proposed. Expand
Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
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It is shown that the molecular structure is preserved during expansion and ultrastructural details of SCs can be revealed, and post-expansion labeling by MAP-SIM improves immunolabeling efficiency and allowed the previously hidden details of the molecular organization ofSCs to be unraveled. Expand
Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
TLDR
The data demonstrate that post-expansion labeling by MAP-SIM improves immunolabeling efficiency and allowed us thus to unravel previously hidden details of the molecular organization of SCs. Expand
Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly
TLDR
The structural basis for self-assembly of human SYCP1, the core architectural element of the meiotic synaptonemal complex, reveals an obligate tetrameric structure that assembles into a zipper-like supramolecular lattice. Expand
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