The three-dimensional structure of invertase (beta-fructosidase) from Thermotoga maritima reveals a bimodular arrangement and an evolutionary relationship between retaining and inverting glycosidases.

@article{Alberto2004TheTS,
  title={The three-dimensional structure of invertase (beta-fructosidase) from Thermotoga maritima reveals a bimodular arrangement and an evolutionary relationship between retaining and inverting glycosidases.},
  author={François Alberto and Christophe Bignon and Gerlind Sulzenbacher and Bernard Henrissat and Mirjam Czjzek},
  journal={The Journal of biological chemistry},
  year={2004},
  volume={279 18},
  pages={
          18903-10
        }
}
Thermotoga maritima invertase (beta-fructosidase) hydrolyzes sucrose to release fructose and glucose, which are major carbon and energy sources for both prokaryotes and eukaryotes. The name "invertase" was given to this enzyme over a century ago, because the 1:1 mixture of glucose and fructose that it produces was named "invert sugar." Despite its name, the enzyme operates with a mechanism leading to the retention of the anomeric configuration at the site of cleavage. The enzyme belongs to… CONTINUE READING

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