The three-dimensional structure of an enzyme molecule.

  title={The three-dimensional structure of an enzyme molecule.},
  author={David C. Phillips},
  journal={Scientific American},
  volume={215 5},
  • D. Phillips
  • Published 1966
  • Physics, Medicine
  • Scientific American
The active site of hen egg-white lysozyme: flexibility and chemical bonding
  • J. Held, S. van Smaalen
  • Physics, Medicine
  • Acta crystallographica. Section D, Biological crystallography
  • 2014
Chemical bonding at the active site of lysozyme is analyzed on the basis of a multipole model employing transferable multipole parameters from a database. Large B factors at low temperatures reflectExpand
Structural Studies of the Bacteriophage Lambda Lysozyme Complexed with a Chitohexasaccharide
Lysozyme from the bacteriophage lambda, laL, complexed with a chitohexasaccharide has been solved to 2.6 Aby molecular replacement using a mutant form of laL as a model. The protein packs as a dimerExpand
Effect of nutritional interventions with quercetin, oat hulls, β-glucans, lysozyme and fish oil on performance and health status related parameters of broilers chickens
It was concluded that the tested nutritional interventions only marginally effected health status related parameters and the genes differently expressed between dietary interventions did not seem to be directly involved in immune related processes. Expand
Accurate modeling of protein conformation by automatic segment matching.
  • M. Levitt
  • Physics, Medicine
  • Journal of molecular biology
  • 1992
The segment match modeling method is fully automatic, yields a complete set of atomic co-ordinates without any human intervention and is efficient (14 s/residue on the Silicon Graphics 4D/25 Personal Iris workstation). Expand
Biomimetic Metamaterial Design Simulation and Evaluation for Building Acoustics by Impedance Measurements
This study investigates the potentials of acoustic metamaterial applications in room and building acoustics by means of impedance tube experiments to assess the effectiveness of such an approach in a possible acoustical design problem. Expand
Functional design of glycan-conjugated molecules using a chemoenzymatic approach.
  • M. Ogata
  • Medicine
  • Bioscience, biotechnology, and biochemistry
  • 2021
This work has established a method for accurately and a large scale synthesis of functional carbohydrates with diverse properties using a unique enzymatic method and several synthetic glycan-conjugated molecules are taken as examples to show design, synthesis and function. Expand
Illuminating Disorder Induced by Glu in a Stable Arg-Anchored Transmembrane Helix
An astonishing induction of disorder is reported when one Glu residue is introduced into a highly stable 23-residue transmembrane helix in a lipid membrane environment and the helix properties change radically to exhibit a multiplicity of three or more disordered states. Expand
Influenza Viruses: Harnessing the Crucial Role of the M2 Ion-Channel and Neuraminidase toward Inhibitor Design
The crux of this review highlights the recent studies on the biology of influenza viruses, focusing on the structure, function, and mechanism of action of the M2 channel and neuraminidase as therapeutic targets, to highlight therapeutic strategies that could be explored further towards the design of novel anti-influenza inhibitors with the ability to inhibit resistant strains. Expand
Novel Structural Annotation and Functional Expression Analysis of GTP_EFTU Conserved Genes in Pepper Based on the PacBio Sequencing Data
  • Bingqian Tang, Xie Lingling, +11 authors Liu Feng
  • Biology
  • 2021
These analyses revealed important structural and functional information for the identified 39 genes that contain GTP_EFTU domains, providing important references for further follow-up experiments to verify the genes function on plants or their unique roles in peppers. Expand