The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes.

@article{Andersson2011TheTZ,
  title={The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes.},
  author={Caroline Andersson and Katrin Larsson and Fariba Vaziri-Sani and Kristian Lynch and Annelie Carlsson and Elisabeth Cedervall and Bj{\"o}rn J{\"o}nsson and Jan Neiderud and Majvi M{\aa}nsson and Anita Nilsson and {\AA}ke Lernmark and Helena Elding Larsson and S-A Ivarsson},
  journal={Autoimmunity},
  year={2011},
  volume={44 5},
  pages={
          394-405
        }
}
AIMS We tested whether autoantibodies to all three ZnT8RWQ variants, GAD65, insulinoma-associated protein 2 (IA-2), insulin and autoantibodies to islet cell cytoplasm (ICA) in combination with human leukocyte antigen (HLA) would improve the diagnostic sensitivity of childhood type 1 diabetes by detecting the children who otherwise would have been autoantibody-negative. METHODS A total of 686 patients diagnosed in 1996-2005 in Skåne were analyzed for all the seven autoantibodies [arginin 325… CONTINUE READING
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