The three SMC sisters

  • Dana Branzei
  • Published 2011 in Nature Reviews Molecular Cell Biology

Abstract

Many tales and quests bring in the concept of three: three heirs, three suitors, three tasks. Throughout the eukaryotic kingdom, three structural maintenance of chromosomes (SMC) complexes — cohesin, condensin and SMC5–SMC6 — are crucial for chromosome reorganization events and cell viability. Each of these complexes consists of SMC heterodimers and… (More)
DOI: 10.1038/nrm3125

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