The three Es of cancer immunoediting.

  title={The three Es of cancer immunoediting.},
  author={Gavin P Dunn and L. John Old and Robert D Schreiber},
  journal={Annual review of immunology},
After a century of controversy, the notion that the immune system regulates cancer development is experiencing a new resurgence. An overwhelming amount of data from animal models--together with compelling data from human patients--indicate that a functional cancer immunosurveillance process indeed exists that acts as an extrinsic tumor suppressor. However, it has also become clear that the immune system can facilitate tumor progression, at least in part, by sculpting the immunogenic phenotype… CONTINUE READING
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