The third replicon of members of the Burkholderia cepacia Complex, plasmid pC3, plays a role in stress tolerance.

@article{Agnoli2014TheTR,
  title={The third replicon of members of the Burkholderia cepacia Complex, plasmid pC3, plays a role in stress tolerance.},
  author={Kirsty Agnoli and Carmen Frauenknecht and Roman Freitag and Stephan Schwager and Christian Jenul and Annette C Vergunst and Aur{\'e}lien Carlier and Leo Eberl},
  journal={Applied and environmental microbiology},
  year={2014},
  volume={80 4},
  pages={1340-8}
}
The metabolically versatile Burkholderia cepacia complex (Bcc) occupies a variety of niches, including the plant rhizosphere and the cystic fibrosis lung (where it is often fatal to the patient). Bcc members have multipartite genomes, of which the third replicon, pC3 (previously chromosome 3), has been shown to be a nonessential megaplasmid which confers virulence and both antifungal and proteolytic activity on several strains. In this study, pC3 curing was extended to cover strains of 16 of… CONTINUE READING
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Molecular mechanisms of chlorhexidine tolerance in Burkholderia cenocepacia biofilms

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