The thioredoxin system of Plasmodium falciparum and other parasites

Abstract

Antioxidant defence plays a crucial role in rapidly growing and multiplying organisms, including parasites and tumor cells. Apart from reactive oxygen species (ROS) produced in endogenous reactions, parasites are usually exposed to high ROS concentrations imposed by the host immune system. The glutathione and thioredoxin systems represent the two major… (More)
DOI: 10.1007/s00018-002-8484-9

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