The thick left ventricular wall of the giraffe heart normalises wall tension, but limits stroke volume and cardiac output

@article{Smerup2016TheTL,
  title={The thick left ventricular wall of the giraffe heart normalises wall tension, but limits stroke volume and cardiac output},
  author={M. Smerup and M. Damkj{\ae}r and E. Br{\o}ndum and U. Baandrup and S. B. Kristiansen and H. Nygaard and J. Funder and C. Aalkj{\ae}r and Cathrine Sauer and Rasmus Buchanan and M. Bertelsen and K. {\O}stergaard and C. Gr{\o}ndahl and G. Candy and J. Hasenkam and N. Secher and P. Bie and T. Wang},
  journal={Journal of Experimental Biology},
  year={2016},
  volume={219},
  pages={457 - 463}
}
ABSTRACT Giraffes – the tallest extant animals on Earth – are renowned for their high central arterial blood pressure, which is necessary to secure brain perfusion. Arterial pressure may exceed 300 mmHg and has historically been attributed to an exceptionally large heart. Recently, this has been refuted by several studies demonstrating that the mass of giraffe heart is similar to that of other mammals when expressed relative to body mass. It thus remains unexplained how the normal-sized giraffe… Expand
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  • 4
  • PDF
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  • 4
Cardiovascular Physiology of Dinosaurs.
  • 10
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  • 2
  • PDF
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  • 6
  • PDF
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  • 7
...
1
2
...

References

SHOWING 1-10 OF 44 REFERENCES
The Principle of Laplace and Scaling of Ventricular Wall Stress and Blood Pressure in Mammals and Birds
  • 93
  • Highly Influential
Left Ventricular Morphology of the Giraffe Heart Examined by Stereological Methods
  • 9
An allometric analysis of the giraffe cardiovascular system.
  • G. Mitchell, J. Skinner
  • Biology, Medicine
  • Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
  • 2009
  • 33
  • Highly Influential
  • PDF
Wall stress and patterns of hypertrophy in the human left ventricle.
  • 2,251
  • Highly Influential
  • PDF
Protection against high intravascular pressure in giraffe legs.
  • 16
  • PDF
Blood flow and pressure in the giraffe carotid artery.
  • 62
  • Highly Influential
Circulation of the Giraffe
  • 83
  • PDF
Pressure profile and morphology of the arteries along the giraffe limb
  • 12
Left Ventricular Tension and Stress in Man
  • 487
...
1
2
3
4
5
...