The thermolability of nuclear protein import in tsBN2 cells is suppressed by microinjected Ran-GTP or Ran-GDP, but not by RanQ69L or RanT24N.

@article{Dickmanns1996TheTO,
  title={The thermolability of nuclear protein import in tsBN2 cells is suppressed by microinjected Ran-GTP or Ran-GDP, but not by RanQ69L or RanT24N.},
  author={Antje Dickmanns and F. Ralf Bischoff and Chris Marshallsay and Reinhard L{\"u}hrmann and Herwig Ponstingl and Ellen Fanning},
  journal={Journal of cell science},
  year={1996},
  volume={109 ( Pt 6)},
  pages={1449-57}
}
The nuclear protein regulator of chromosome condensation 1 (RCC1) stimulates guanine nucleotide exchange on a protein, Ran, that is required for nuclear protein import. In the present report, we confirm that RCC1 is also required for nuclear protein import in tsBN2 hamster cells in vivo. The thermolability of nuclear protein import in tsBN2 cells was… CONTINUE READING