The thermodynamics of virus capsid assembly.

  title={The thermodynamics of virus capsid assembly.},
  author={Sarah P. Katen and Adam Zlotnick},
  journal={Methods in enzymology},
Virus capsid assembly is a critical step in the viral life cycle. The underlying basis of capsid stability is key to understanding this process. Capsid subunits interact with weak individual contact energies to form a globally stable icosahedral lattice; this structure is ideal for encapsidating the viral genome and host partners and protecting its contents upon secretion, yet the unique properties of its assembly and inter-subunit contacts allow the capsid to dissociate upon entering a new… CONTINUE READING
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