The therapeutic potential of targeting the EGFR family in epithelial ovarian cancer

@inproceedings{Sheng2011TheTP,
  title={The therapeutic potential of targeting the EGFR family in epithelial ovarian cancer},
  author={Qiu Sheng and Jia-ren Liu},
  booktitle={British Journal of Cancer},
  year={2011}
}
The epithelial growth factor receptor (EGFR) family of receptor tyrosine kinases has been reported to have an active role in a number of malignancies. Amplifications and overexpression of various EGFR family members, including EGFR, Her2, and ErbB3, have been reported in epithelial ovarian cancer. Although anti-EGFR-targeted therapy has shown limited clinical activity in ovarian cancer to date, a recent report suggests that activation of ErbB3, one of the members of the EGFR family, may support… CONTINUE READING